Creamy Mayo-Parmesan Keto Chicken Thighs Recipe

These mayo-Parmesan keto chicken thighs are juicy, flavorful, and simple to prepare — a true “winner winner chicken dinner” every time.

This recipe combines a savory spice blend with a creamy mayonnaise topping and plenty of freshly grated Parmesan for a low-carb chicken dish the whole family will enjoy. It’s an easy, reliable addition to your rotation of weeknight dinners or weekend meals.

Seasonings for the chicken thighs

The spice mix used here is simple and balanced: equal parts garlic powder, Italian seasoning, onion powder, paprika, salt, and pepper. A small trick to season evenly is to spray the baking pan, sprinkle about one-third of the spice mix across the bottom, then place the chicken skin-side up and press each piece gently into the spices to season the undersides. Finish by sprinkling the remaining seasoning over the tops. This method seasons the chicken thoroughly while minimizing handling of raw meat.

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Topping and cheese choices

The mayonnaise mixture gets a bright lift from Dijon mustard and a touch of prepared horseradish; both add depth without extra carbs. If you prefer, substitute yellow or spicy mustard depending on your taste. Prepared horseradish (horseradish root with vinegar and salt) is convenient, but fresh homemade horseradish also works. Using freshly grated Parmesan yields the best texture and flavor — it’s quick to grate and avoids the anti-caking additives sometimes found in pre-grated varieties.

Difficulty and tips

This dish looks and tastes impressive but is very easy to make. The spice mixture and the mayo-Parmesan topping create a flavorful, slightly crispy finish while keeping the recipe low-carb. Spread the mayo mixture over the thighs and sprinkle additional grated Parmesan on top to form a savory crust during baking. Cook until the internal temperature reaches 165°F (74°C), about 50–70 minutes depending on oven and chicken size.

Suggested side dishes

Pair these chicken thighs with low-carb vegetable sides for a complete meal. Roasted or sautéed greens, mashed turnips, or roasted radishes complement the rich flavors and keep the meal keto-friendly.

Helpful Hints:

* Dijon mustard adds depth, but yellow or spicy mustard are fine substitutes.

* Use prepared horseradish for convenience or homemade for a fresher flavor.

Main kitchen equipment and utensils

• 13×9 inch baking pan
• Measuring cups
• Measuring spoons

Encouragement

***The LORD is my strength and my shield; My heart trusted in Him, and I am helped; Therefore my heart greatly rejoices, And with my song I will praise Him. Psalm 28:7***

Mayo-Parmesan Keto Chicken Thighs

Yield:
6 Servings

Prep Time:
15 minutes

Cook Time:
1 hour

Total Time:
1 hour 15 minutes

These mayo-Parmesan keto chicken thighs are juicy and full of flavor — easy enough for weeknights and special enough for guests.

Ingredients

• Avocado oil spray
• ¼ teaspoon garlic powder
• ¼ teaspoon Italian seasoning
• ¼ teaspoon onion powder
• ¼ teaspoon paprika
• ¼ teaspoon salt
• ¼ teaspoon pepper
• 6 bone-in, skin-on chicken thighs
• 1 cup keto mayonnaise
• 2 tablespoons Dijon mustard
• 1 tablespoon prepared horseradish
• ½ cup freshly grated Parmesan cheese, divided

Instructions

1. Preheat oven to 350°F (175°C). Spray a 13×9-inch baking pan with avocado oil spray and set aside.
2. In a small bowl, combine garlic powder, Italian seasoning, onion powder, paprika, salt, and pepper.
3. Sprinkle one-third of the spice mixture across the bottom of the prepared pan.
4. Place the chicken thighs in the pan, skin side up, pressing each piece down slightly to season the underside.
5. Sprinkle the remaining two-thirds of the spice mixture evenly over the tops of the chicken thighs.
6. In a small bowl, mix mayonnaise, Dijon mustard, and horseradish. Stir in ¼ cup of the grated Parmesan.
7. Spread the mayonnaise mixture evenly over the chicken thighs and sprinkle the remaining ¼ cup Parmesan over the top.
8. Bake uncovered until the chicken reaches an internal temperature of 165°F (74°C), about 50–70 minutes depending on size.

Nutrition Information:

Yield: 6
Serving Size: 1 chicken thigh

Amount Per Serving:
Calories: 582Total Fat: 48gSaturated Fat: 13gTrans Fat: 0gUnsaturated Fat: 33gCholesterol: 50mgSodium: 655mgCarbohydrates: 0gFiber: 0gSugar: 0gProtein: 23g

Nutrition estimates provided as a courtesy. Values vary with brands and portion sizes.

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